Genes and cardiovascular risk

Genes and cardiovascular risk.

If DNA really is the ‘blueprint’ for life, how can genetic analysis fail to tell us what life has in store for us? One of two excellent articles in this journal shows us that the usual way to calculate risk of cardiovascular disease, such as ascertaining smoking habits and measuring blood pressure and cholesterol, is better than analyses for commonly occurring variations in DNA sequences. From ...

Genes encoding fibrinogen and cardiovascular risk.

The role of fibrinogen in cardiovascular disease has been extensively studied, and meta-analyses have definitively confirmed that high levels of fibrinogen are associated with an increased risk of the disease. In recent years, several polymorphisms have been identified in the fibrinogen chain genes that contribute to determine the levels of fibrinogen in the general population. The fibrinogen b...

Genes, environment, and cardiovascular disease.

In this essay, we call to attention what every medical researcher knows about the etiology of cardiovascular disease but most deny, or choose to ignore, when designing, carrying out, and reporting genetic studies. Medical research is entering an era of synthesis that will take advantage of the successes of reductionism over the past decade in defining and describing human genome variations. Mea...

androgen deprivation therapy and cardiovascular risk

Knowledge and Attitude on Cardiovascular Disease Risk Factors and Their Relationship with Obesity and Biochemical Parameters

Background: According to the high prevalence of cardiovascular diseases (CVDs) in developing countries as well as high treatment expenses for patients and health-care systems, CVDs prevention in such societies has a great importance. One of the most effective strategies is improvement of knowledge and attitude towards the CVDs risk factors. This study aimed to evaluate the knowledge and attitud...